Vinca and Catharanthus plant extracts and their therapeutic potential applications

This interdisciplinary doctoral thesis (Vinca and Catharanthus plant extracts and their therapeutic potential applications) unites and develops subjects related to newly discovered information and wellknown facts, regarding the pharmacological potential of hydroalcoholic leaf extracts. The plant species studied in this research work belong to Vinca L. genus (periwinkle), like Vinca minor L., Vinca major L., Vinca herbacea Waldst. & Kit., and the culture variety Vinca major L. var. variegata Louden; a Catharanthus genus hybrid (Catharanthus roseus (L.) G. Don cv. Pacifica); and Chelidonium majus L. species (celandine). In order to ascertain the key distinctions or similarities between these plant species, the morphological, anatomical, and ultrastructural characteristics of the leaves of Vinca and Catharanthus roseus were examined. The composition of the plant extracts, antioxidant properties, antibacterial potential, in vitro cytotoxicity against human cell lines, and green metal nanoparticle formation were also determined.